A preoperative metabolic marker of parkinsonian apathy following subthalamic nucleus stimulation.
Identifieur interne : 000021 ( France/Analysis ); précédent : 000020; suivant : 000022A preoperative metabolic marker of parkinsonian apathy following subthalamic nucleus stimulation.
Auteurs : Aude Gesquière-Dando [France] ; Eric Guedj [France] ; Anderson Loundou [France] ; Romain Carron [France] ; Tatiana Witjas [France] ; Frédérique Fluchère [France] ; Marie Delfini [France] ; Laura Mundler [France] ; Jean Regis [France] ; Jean-Philippe Azulay [France] ; Alexandre Eusebio [France]Source :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2015.
Abstract
Subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson's disease (PD) has been associated with the development of postoperative apathy. Debate on the causes of postoperative apathy continues, and the dominant hypothesis is that stimulation or dopaminergic drug reductions are causal in its development. We hypothesized that a preoperative predisposition to apathy also could exist. To this end, we sought to identify a preoperative metabolic pattern using [(18) ]Fluorodeoxyglucose Positron Emission Tomography (PET), which could be associated with the occurrence of postoperative apathy after STN-DBS for PD.
DOI: 10.1002/mds.26349
PubMed: 26228098
Affiliations:
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pubmed:26228098Le document en format XML
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type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName></affiliation></author><author><name sortKey="Delfini, Marie" sort="Delfini, Marie" uniqKey="Delfini M" first="Marie" last="Delfini">Marie Delfini</name><affiliation wicri:level="4"><nlm:affiliation>APHM, CHU Timone, Department of Neurology and Movement Disorders, Aix Marseille Université, Marseille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>APHM, CHU Timone, Department of Neurology and Movement Disorders, Aix Marseille Université, Marseille</wicri:regionArea><placeName><settlement type="city">Marseille</settlement></placeName><orgName type="university">Université d'Aix-Marseille</orgName><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName></affiliation></author><author><name sortKey="Mundler, Laura" sort="Mundler, Laura" uniqKey="Mundler L" first="Laura" last="Mundler">Laura Mundler</name><affiliation wicri:level="4"><nlm:affiliation>APHM, CHU Timone, Department of Neurology and Movement Disorders, Aix Marseille Université, Marseille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>APHM, CHU Timone, Department of Neurology and Movement Disorders, Aix Marseille Université, Marseille</wicri:regionArea><placeName><settlement type="city">Marseille</settlement></placeName><orgName type="university">Université d'Aix-Marseille</orgName><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName></affiliation></author><author><name sortKey="Regis, Jean" sort="Regis, Jean" uniqKey="Regis J" first="Jean" last="Regis">Jean Regis</name><affiliation wicri:level="4"><nlm:affiliation>APHM, CHU Timone, Department of Functional and Stereotactic Neurosurgery, Aix Marseille Université, Marseille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>APHM, CHU Timone, Department of Functional and Stereotactic Neurosurgery, Aix Marseille Université, Marseille</wicri:regionArea><placeName><settlement type="city">Marseille</settlement></placeName><orgName type="university">Université d'Aix-Marseille</orgName><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName></affiliation></author><author><name sortKey="Azulay, Jean Philippe" sort="Azulay, Jean Philippe" uniqKey="Azulay J" first="Jean-Philippe" last="Azulay">Jean-Philippe Azulay</name><affiliation wicri:level="4"><nlm:affiliation>APHM, CHU Timone, Department of Neurology and Movement Disorders, Aix Marseille Université, Marseille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>APHM, CHU Timone, Department of Neurology and Movement Disorders, Aix Marseille Université, Marseille</wicri:regionArea><placeName><settlement type="city">Marseille</settlement></placeName><orgName type="university">Université d'Aix-Marseille</orgName><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName></affiliation></author><author><name sortKey="Eusebio, Alexandre" sort="Eusebio, Alexandre" uniqKey="Eusebio A" first="Alexandre" last="Eusebio">Alexandre Eusebio</name><affiliation wicri:level="4"><nlm:affiliation>APHM, CHU Timone, Department of Neurology and Movement Disorders, Aix Marseille Université, Marseille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>APHM, CHU Timone, Department of Neurology and Movement Disorders, Aix Marseille Université, Marseille</wicri:regionArea><placeName><settlement type="city">Marseille</settlement></placeName><orgName type="university">Université d'Aix-Marseille</orgName><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName></affiliation></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson's disease (PD) has been associated with the development of postoperative apathy. Debate on the causes of postoperative apathy continues, and the dominant hypothesis is that stimulation or dopaminergic drug reductions are causal in its development. We hypothesized that a preoperative predisposition to apathy also could exist. To this end, we sought to identify a preoperative metabolic pattern using [(18) ]Fluorodeoxyglucose Positron Emission Tomography (PET), which could be associated with the occurrence of postoperative apathy after STN-DBS for PD.</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Provence-Alpes-Côte d'Azur</li></region><settlement><li>Marseille</li></settlement><orgName><li>Université d'Aix-Marseille</li></orgName></list><tree><country name="France"><noRegion><name sortKey="Gesquiere Dando, Aude" sort="Gesquiere Dando, Aude" uniqKey="Gesquiere Dando A" first="Aude" last="Gesquière-Dando">Aude Gesquière-Dando</name></noRegion><name sortKey="Azulay, Jean Philippe" sort="Azulay, Jean Philippe" uniqKey="Azulay J" first="Jean-Philippe" last="Azulay">Jean-Philippe Azulay</name><name sortKey="Carron, Romain" sort="Carron, Romain" uniqKey="Carron R" first="Romain" last="Carron">Romain Carron</name><name sortKey="Delfini, Marie" sort="Delfini, Marie" uniqKey="Delfini M" first="Marie" last="Delfini">Marie Delfini</name><name sortKey="Eusebio, Alexandre" sort="Eusebio, Alexandre" uniqKey="Eusebio A" first="Alexandre" last="Eusebio">Alexandre Eusebio</name><name sortKey="Fluchere, Frederique" sort="Fluchere, Frederique" uniqKey="Fluchere F" first="Frédérique" last="Fluchère">Frédérique Fluchère</name><name sortKey="Guedj, Eric" sort="Guedj, Eric" uniqKey="Guedj E" first="Eric" last="Guedj">Eric Guedj</name><name sortKey="Loundou, Anderson" sort="Loundou, Anderson" uniqKey="Loundou A" first="Anderson" last="Loundou">Anderson Loundou</name><name sortKey="Mundler, Laura" sort="Mundler, Laura" uniqKey="Mundler L" first="Laura" last="Mundler">Laura Mundler</name><name sortKey="Regis, Jean" sort="Regis, Jean" uniqKey="Regis J" first="Jean" last="Regis">Jean Regis</name><name sortKey="Witjas, Tatiana" sort="Witjas, Tatiana" uniqKey="Witjas T" first="Tatiana" last="Witjas">Tatiana Witjas</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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